The programme hears from researchers who have identified some 400 'legal highs' - a finding which asks profound questions of the way society seeks to control drug use.
News, sport, weather and travel information with Rhun ap Iorwerth and Sarah Dickins.
Jamie and Louise are joined by their green-fingered guru Terry Walton to answer your gardening questions.
Jason Mohammad introduces listener debate on the top stories of the day.
Frank Hennessy looks forward to Celtic Heartbeat, there's the Wednesday Word, and Robert Atkins chats to Roy about busking.
Drivetime news, sport, weather and travel with Felicity Evans and Oliver Hides.
Derek Brockway continues his travels around the the Welsh countryside. Expect a pleasing mix of history, weather facts, light hiking and humour from Derek and the team.
Music sessions, tips on hot venues and behind-the-scenes gossip with a mix of music and chat reflecting the rich Welsh cultural scene.
Adam Walton takes a closer look at the newspaper headlines which seem to link a huge variety of different foods and activities with cancer.
Join the club for music and chat.
BBC Radio Wales joins the BBC World Service for a selection of news and current affairs, science and arts programmes to take you through the night.