Supermarket manager Calvin tries to overcome his soul-destroying stammer, and 24-year-old Ayesha pursues her dreams of becoming a police officer. Show more

Self-taught chef Thuy vies for first place in Gok Wan’s national restaurant awards, and diabetic Abigail waits to hear if she’ll receive treatment that could save her life. Show more

Alicia and Dexter struggle with the gruelling process of IVF, having failed twice before, and construction engineer Gary is desperate to kick start his new gin business. Show more

After developing multiple sclerosis, ex-railway worker Simon finds out if man’s best friend can help restore his independence. Show more

Andrea discovers if her life-threatening cancer has returned, while deli worker Jamie is determined to be crowned the best musical comedian in the UK. Show more

Mum-of-four Rachel undergoes high-risk bowel surgery which could save her life, and trainee pilot Robbie competes for a one-of-a-kind aerobatics scholarship. Show more

Former West End star Brodie tries to get into one of the UK's top ballet schools, and Nelema, who was born severely deaf, takes her driving test in a bid to get her dream job. Show more

After suffering from a serious stroke, car enthusiast Peter is determined to get back in the driving seat, and local hero Colin tries to get a community wind farm up and running Show more

Teenager Kate undergoes a genetic test for Huntington’s disease, and horse enthusiast Charley attempts to achieve her dreams of becoming a professional horse-riding coach. Show more

Batuhan, who has muscular dystrophy, takes his driving test in an attempt to gain independence, and the villagers of Cheavely in Cambridgeshire try to save their local church. Show more

Series following people as they go through extraordinary life-changing moments. After becoming deaf, violinist Carol undergoes surgery which could potentially restore her hearing. Show more

Series following people as they go through extraordinary life-changing moments. Amreeta undergoes intricate surgery in an attempt to regain her sight. Show more

Series following people as they go through extraordinary life-changing moments, including Gary, who tries for the last time to become a London cabbie after 32 failed attempts. Show more

Series following people as they go through extraordinary life-changing moments. The villagers of South Moreton discover if they can save their village pub from developers. Show more

Series following people as they go through extraordinary life-changing moments, including Mark, who is finding out if his life-threatening cancer has returned. Show more