Overweight Brits Bex Upton and Anne Odeke aren't slimming, so will living with 38-stone Deloris and her 23-stone sister Diane in Mississippi make them want to fight the flab? Show more

Overweight Brits Gary and Amareen aren't slimming, so will living with a morbidly obese family on Crete make them think about changing their out-of-control ways? Show more

Will living with obese families in the most notorious slums of Buenos Aires be the wake-up call overweight Brits Lauren and Dan need to begin trying to lose the pounds? Show more

Will witnessing the effects of living an ultra-lazy lifestyle in Kuwait and meeting a 51-stone recluse get overweight Brits Carley and Darran to change their unhealthy ways? Show more

Renowned broadcaster and satirist David Frost talks about his life and career.

Mark Lawson talks to AS Byatt after her Booker Prize nomination for The Children's Book. Byatt talks about her passion for literature and how she combines family life with writing. Show more

Mark Lawson talks to explorer Sir Ranulph Fiennes about his life's work, as Fiennes reveals the ingredients behind his incredible determination and exploits. Show more

Mark Lawson talks to actor Timothy Spall about his life and career. Spall reflects on his working-class roots, on being a 'professional depicter' and his fight with leukaemia. Show more

Mark Lawson talks to Oscar-winning actress Vanessa Redgrave about her life and career. She reflects on her acting family, political activism and the loss of her daughter Natasha. Show more