A round-up of the day's news, sport and business stories, and a look at the morning's papers.
News and insight from the business world with Andrew Verity and Mickey Clark, plus updates on the morning's news. Show more
Former Science Minister Lord Drayson says people will die if airlines stop importing animals for research - and David Cameron talks Afghanistan and Syria with Barack Obama. Show more
Do you support animal testing? The former Science Minister, Lord Drayson, says 'people will suffer and die' if a new campaign by animal rights protestors succeeds. Show more
The High Court rules Met police officers assaulted a 16 year old boy with serious autism, forcing him into handcuffs during a school trip. Victoria speaks to the family solicitor. Show more
Anna Foster sits in for Shelagh, with live coverage of David Cameron's official welcome from President Obama at the White House, plus Prime Minister's Questions from Westminster. Show more
John Inverdale hosts coverage of the second day of the 2012 Cheltenham festival. With commentary of the day's big races including the Queen Mother Champion Steeple Chase.
Harrowing reports from Switzerland where 28 people - mostly childen - die in a coach crash. Show more
Mark Pougatch presents has all the day's sports news and build-up to Champions League action, with Chelsea facing Napoli in their return leg.
Live football commentary of Chelsea v Napoli in their second leg clash in the Champions League last 16 round as the Londoners bid to overcome a 3-1 deficit.
Tony discusses Cameron in the US, and why tube workers rejected a new pay offer. Also a specially extended Tony's Team Talk. Tony and guests don the shirt of hurt for Sport Relief. Show more
Just how special is the 'special relationship' between the US and UK. An ex-serviceman affected by nuclear testing shares his story and Dr Karl with your questions. Show more
