- Writer:
- Nigel Kneale
- Producer:
- Rudolph Cartier
- Settings:
- Stewart Marshall
- Professor Bernard Quatermass, Head of the British Experimental Rocket Group:
- Reginald Tate
- Judith Carroon, Chief Assistant to Quatermass:
- Isabel Dean
- Victor Carroon:
- Duncan Lamont
- Dr. Gordon Briscoe:
- John Glen
- Detective-Inspector Lomax:
- Ian Colin
- Detective-Sergeant Best:
- Frank Hawkins
- John Paterson, senior engineer:
- Hugh Kelly [character's surname billed as 'Patterson']
- James Fullalove, chief columnist of the Daily Gazette:
- Paul Whitsun-Jones
- News Editor of the Daily Gazette:
- Oliver Johnston
- American reporter:
- Philip Vickers
- Miss Wilde:
- Katie Johnson
- Walters:
- Lewis Wilson
- Photographer:
- Darrell Runey
- Ramsay:
- Jack Rodney
- Boy:
- Anthony Green
- Chemist:
- Richard Cuthbert
- Cinema manager:
- Lee Fox
- Cinemagoer:
- Janet Joye
- Usherette:
- Bernadette Milnes
- 'Space Lieutenant':
- Keith Herrington
- 'Space Girl':
- Pauline Johnson