General practitioner Dr Martin Hughes examines some common medical problems and follows patients as they seek treatment. Annette Callum is desperate to become a mother, and as she approaches her 40th birthday she is aware that time is running out. After ten years of fertility treatment and five failed attempts to have a test-tube baby, she and her partner Hani decide to have one final try. It has cost them thousands of pounds so far but they believe it to be money well spent. The Casebook team follows the Cambridge couple through their sixth IVF treatment. Producer John Hayes Fisher Series editor Michael Latham