- Writer:
- Nigel Kneale
- Producer:
- Rudolph Cartier
- Settings:
- Richard R. Greenough
- Professor Bernard Quatermass:
- Reginald Tate
- Judith Carroon:
- Isabel Dean
- Victor Carroon:
- Duncan Lamont
- John Paterson:
- Hugh Kelly
- Dr. Gordon Briscoe:
- John Glen
- Detective Inspector Lomax:
- Ian Colin
- Detective-Sergeant Best:
- Frank Hawkins
- James Fullalove:
- Paul Whitsun-Jones
- Chemist:
- Richard Cuthbert
- Boy:
- Anthony Green
- Usherette:
- Bernadette Milnes
- Janet:
- Christie Humphrey
- Ted:
- John Stone
- Park keeper:
- Frank Atkinson
- Police Inspector:
- Reginald Hearne
- A drunk:
- Wilfred Brambell
- Sir Vernon Dodds:
- John Kidd
- Of a Television Outside Broadcast Unit - Producer:
- Tony van Bridge
- Of a Television Outside Broadcast Unit - Commentator:
- Neil Arden
- Of a Television Outside Broadcast Unit - Secretary:
- Josephine Crombie
