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The Evidence

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Claudia Hammond joins scientists and experts to explore science’s effect on our world

Claudia Hammond joins scientists and experts to explore the effect science has on the world around us

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The Evidence: Coronavirus: The Evidence: Drug-resistant superbugs

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Drug-resistant superbugs

26/02/2022 GMT

Coronavirus: The Evidence

BBC World Service - The Evidence, Coronavirus: The Evidence, Drug-resistant superbugs

The silent pandemic - drug resistant infections threaten the future of modern medicine

Anti-microbial resistance or drug-resistant infections play a part in the deaths of five million adults and children every year. How do we stop the rise and rise of the superbug?

Today, Claudia Hammond and her panel of experts focus on what’s been called “the silent pandemic”, the threat to modern medicine of anti-microbial resistance or AMR.

Infections are increasingly resistant to life-saving drugs like antibiotics and many believe the very future of modern medicine is hanging in the balance.

In a series produced in collaboration with Wellcome Collection, this edition of The Evidence is recorded in front of a live audience in the Reading Room at Wellcome Collection in London.

Just last month, a new global study covering 204 countries and territories published in The Lancet reveals the scale of AMR to human health. The number of lives lost is double previous estimates.

The latest data reveals 1.3 million deaths caused directly by resistant infections in just one year, 2019, and five million more deaths were linked with AMR. 

The figures are shocking, especially because one in every five deaths were in children, under five years old, with the highest number of deaths in Western Sub-Saharan Africa.

But this is a pandemic that threatens everybody, wherever they live. 

Everly Macario a public health researcher from Chicago in the United States shares her family’s story: the death of their 18 month old son, Simon, to a drug-resistant strain of the bacterial infection MRSA (Methicillin-resistant Staphylococcus aureus). The loss of Simon spurred Everly to campaign against the mis-use of antibiotics, particularly in agriculture and farming, which contributes to the rise in AMR.

Leaders in the global fight against AMR join Claudia to discuss the threat to human health and address the paradox that while AMR claims millions of lives, so many die each day because they can’t get access to basic, life-saving drugs like antibiotics. 

And Wellcome Collection’s Research Development Lead, Ross Macfarlane, delves into the archives and shares the warning from the inventor of the first antibiotic, penicillin, Alexander Fleming as he accepted his Nobel Prize in 1945, that mis-use would lead to resistance developing.

The new super drug was destined to spawn the new super bug.

Claudia’s guests include the UK Special Envoy on AMR, Professor Dame Sally Davies; the World Health Organisation’s Assistant Director General for Anti-Microbial Resistance, Dr Hanan Balkhy; Senior Research Manager for Drug Resistant Infections at Wellcome, Dr Janet Midega and the Director of ReAct Africa, Dr Mirfin Mpundu.

Produced by: Fiona Hill, Anand Jagatia and Maria Simons 
Studio Engineers: Duncan Hannant and Emma Harth

Picture: Professor Alexander Fleming, Discoverer of Penicillin', 1943, Credit: Daily Herald Archive/Getty Images

The Evidence: Coronavirus: The Evidence

Magazines & Reviews

Claudia Hammond is joined by experts to answer questions about the coronavirus Covid-19.

In The Evidence Claudia Hammond is joined by an expert scientific panel to answer questions from the audience on a variety of aspects of the coronavirus and Covid 19, from the impact of lockdowns and self isolation on the spread of the disease, to the question of who should be tested and the search for treatments. 
Professor Vivek Jha, Executive Director, of the George Institute for Global Health, India, talks about the situation in his country where a lockdown was announced four hours before it began.

Dr Lyndsey Broadbent, a virologist at Queens University Belfast in Northern Ireland, explains what is now known about the biology of the virus and why it causes serious disease in some people and no symptoms in others. 
Christos Lynteris, a medical anthropologist from St Andrews University, discusses the issue of stigma that’s being experienced by some people who have had Covid-19. 

Claudia also hears from a psychiatrist at the University of Verona in northern Italy, which has taken the brunt of cases in the country about some of the most serious consequences for doctors and nurses, and the general population.

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