- Unknown:
- Percy Bysshe Shelley
- Produced By:
- Sir Lewis Casson
- Conducted By:
- Antony Hopkins
- Count Francesco Cenci:
- Robert Farquharson
- His sons: Giacomo:
- Hugh Manning
- Bernardo:
- Stella Chapman
- Cardinal Camillo:
- Harcourt Williams
- Orsino, a prelate:
- Dennis Arundell
- Savella, the Pope's Legate:
- Peter Creswell
- Prince Colonna:
- Charles Maunsell
- Assasins: Olimpio:
- Harry Cooper
- Marzio:
- Robert Rietty
- Judge:
- Denys Blakelock
- An officer:
- Andrew Churchman
- Lucretia, wife of Cenci and step-mother of his children:
- Sybil Thorndike
- Beatrice, his daughter:
- Rosalie Crutchley
- Narrator:
- Lewis Casson